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Department of descriptive and clinical anatomy

SCIENTIFIC WORK

Responsible employee

Lakhtadir TV, Ph.D., Associate Professor, anatomi@ukr.net, 0932014141

“Morphological features and changes of the digestive system in experimental burn skin trauma”, № state registration 0119U101618

Main directions of work

The object of the study – the differences of destructive, compensatory-adaptive and regenerative changes in the Pierre plaques of white male rats after burn injury, depending on the time after the burn and the performed pharmacotherapy with various infusion solutions; structural manifestations of alterative, compensatory-adaptive and regenerative processes in the cortical substance of rat kidneys after experimental burn trauma to the skin, depending on the applied pharmacotherapy with different infusion solutions.

The aim of the work is to model the influence of experimental burn skin trauma on the structural reorganization of functionally different organs in animals, which will optimize effective etiotropic and pathogenetic therapy in patients with skin burn trauma.

Research methods – macroscopic method – for visual determination of the digestive system of rats with burn injury and without burn injury (which was performed by intravenous infusion) and intact rats; histological methods – to establish microstructural changes of Pierre’s plaques in experimental rats; electron microscopic method – to determine the ultrastructural signs of destructive and reactive changes in the cells of the Pierre plaques of experimental rats, statistical method – to determine the changes in the average cross-sectional area of the blood capillaries of the Pierre plaques of experimental rats.

It is established: structural differences of damage and compensatory-adaptive changes of rats at different times after experimental skin burn of II II III degree under conditions of intravenous infusion of 0.9% sodium chloride solution and complex hyperosmolar solutions. It is established that the general manifestation of structural changes in rats with burn trauma is necrosis and apoptosis of functionally different cells, which occur against the background of pronounced changes in the hemo- and lymphomicrocirculatory system. It was found that the manifestation of the initiation of the membrane-plastic effect of Lactoprotein with sorbitol is its impregnation through the damaged wall of blood capillaries and venules of Pierre plaques of rats with burn trauma visualized by electron microscopic examination. The membranoplastic effect of Lactoprotein with sorbitol is manifested in the “exclusion” from the hemomicrocirculation of a number of blood capillaries, due to the formation of dense circular membrane structures that act as a closure, helping to close the vascular lumen. Infusion of Lactoprotein with sorbitol helps to maintain the normal structure of the nodular lymphatic capillaries. The difference between the perinodular lymphatic capillaries in burnt rats infused with a solution of Lactoprotein with sorbitol is that they are mainly full of normal lymphocytes, cells in a state of mitosis, dendritic cells, apoptotic cells and apoptotic cells and apoptosis. Infusion of the solution of Hecoton solution to roasted rats is not accompanied by the phenomenon of “overflow”, which is another positive advantage of its action.

The main provisions of the study are introduced into the educational process at the departments: normal human anatomy Lviv NMU. Danylo Halytsky (Minutes №8 of February 19, 2018); human anatomy of Odessa NMU (protocol №10 from 15.02.2018); human anatomy and histology of the medical faculty of Uzhhorod National University (protocol №8 dated 15.02.2018); anatomy, topographic anatomy and operative surgery of Bukovynian State Medical University (protocol №14 dated March 5, 2018); topographic anatomy and operative surgery of Vinnytsia NMU named after E. Pirogov (protocol №2 dated 13.02.2018); pathological anatomy of Bukovynian State Medical University (protocol №11 dated March 13, 2018); histology of Vinnytsia NMU. E. Pirogov (Minutes №7 of February 15, 2018); human anatomy Vinnytsia NMU. E. Pirogov (protocol №10 dated February 7, 2018)

PUBLISHING ACTIVITY

	V.G. Cherkasov, I.Y. Gerasymuk, A.S. Golovatsky, O.V. Kovalchuk, B.Y. Reminetskyy HUMAN ANATOMY Vinnitsa: Nova kniga 2019, 470 p. Recommended by the Ministry of Health of Ukraine as a textbook for foreign students of higher medical educational institutions of the V level of accreditation
	Human anatomy: textbook: in 3 vols. Vol. 1 / [A.S. Holovatsky, V.G. Cherkasov, М.Р. Sapin et al.]. – Type.3. – Vinnytsia: New book, 2013, 368 p. – IlI. Recommended by the Ministry of Health of Ukraine as a textbook for students of higher medical educational institutions of the V level of accreditation. The publication was prepared in accordance with the order of the Ministry of Health of Ukraine dated 22.06.2010. №502 as the only national textbook. The first volume of the textbook presents modern data on the structure of cells and tissues. The characteristic of bodies, systems and devices of bodies is given. The main stages of human development in ontogenesis, features of structure, growth and development of an organism are described. The functional anatomy of skeletal bones, their joints and the human muscular system is described in detail. A brief description of the blood supply, blood and lymph outflow from these anatomical structures and their innervation is given. Summary tables will help in better mastering the material. At the end of each section of the textbook there are questions for repetition and self-control, which allow you to better understand what you read. All anatomical terms are given in Ukrainian and Latin and correspond to the International Anatomical Nomenclature (São Paulo, 1997) – the Ukrainian standard (Kyiv, 2001). The textbook is intended for students and teachers of higher medical educational institutions of the I V level of accreditation.
	Golovatsky A.S., Cherkasov V.G., Sapin M.R., Parakhin A.I. Human anatomy. In three volumes. Volume two / Edited by V.G. Cherkasov and A.S. Holovatsky. – Vinnytsia: Nova Kniga, 2016, 456 p. IV. The second volume of the textbook presents modern data on the structure of the viscera, central nervous system and senses. The characteristic of bodies, systems and devices of bodies, the characteristic of blood supply, outflow of blood and lymph from these anatomic structures and their innervation is given. Summary tables will help in better mastering the material. At the end of each section of the textbook there are questions for repetition and self-control, which allow you to better understand what you read. All anatomical terms are given in Ukrainian and Latin and correspond to the International Anatomical Nomenclature (São Paulo, 1997) – the Ukrainian standard (Kyiv, 2001). The textbook is intended for students and teachers of higher medical educational institutions of the I V level of accreditation
	Golovatsky A.S., Cherkasov V.G., Sapin M.R., Parakhin A.I. Human anatomy. In three volumes. Volume three. – Vinnytsia: New book, 2017. – 376p.: IV. The third volume of the textbook presents current data on the structure of the peripheral nervous system and cardiovascular system. Summary tables will help in better mastering the material. At the end of each section of the textbook there are questions for repetition and self-control, which allow you to better understand what you read. All anatomical terms are given in Ukrainian and Latin and correspond to the International Anatomical Nomenclature (São Paulo, 1997) – the Ukrainian standard (Kyiv, 2001). The textbook is designed for students and teachers of higher medical educational institutions of the I V level of accreditation.
	Cherkasov V.G., Dzevulskaya I.V., Kovalchuk O.I. Human anatomy (control over independent preparation for practical classes) ./ 5th edition. – Kyiv, 2014. – 172 p. Recommended by the Ministry of Education and Science of Ukraine as a textbook for students of higher medical educational institutions of the I V level of accreditation. The proposed manual provides an active, creative principle of learning the material and should ensure the success of learning and optimization of the assessment system of independent student work.
	Cherkasov V.G., Dzevulska I.V., Kovalchuk O.I. Human anatomy (control over independent preparation for practical classes) Edition 3-e.-Kyiv, 2013. – 69 p. The proposed manual provides an active, creative principle of learning the material and should ensure the success of learning and optimization of the assessment system of independent student work. Each page of the manual contains formalized tasks: to draw letter designations on drawings and in schemes in different (but corresponding) colors; will fill in the tables with the corresponding anatomical terms, equivalents and necessary data. In the process of completing the tasks, the student creates his own textbook on human anatomy, which he can use to study physiology, pathological physiology, pharmacology, other disciplines and in their further professional activities.
	International anatomical terminology (Latin, Ukrainian, Russian and English equivalents). Cherkasov V.G., Bobrik I.I., Guminsky Y.Y., Kovalchuk O.I. / Ed. V.G. Cherkasov. – Vinnytsia: New book, 2010. – 392 p. Recommended by the Central Methodical Office for Higher Medical Education of the Ministry of Health of Ukraine as a textbook for students of higher medical educational institutions of the I V level of accreditation For the first time, a list of Latin, Ukrainian, Russian and English equivalents of anatomical terms of the latest Latin-English (Stuttgart – New York, 1998), Ukrainian (Kyiv, 2001) and Russian (Moscow, 2003) anatomical nomenclatures was created.
	Johannes Sobotta Atlas of Human Anatomy. Tutorial. In two volumes. Edited by R. Putz and R. Pabst. Re-editing and editing of the Ukrainian edition by V.G. Cherkasov. Translated by O.I. Kovalchuk. Volume 2. Trunk, internal organs, lower extremity. – Kyiv, “Ukrainian Medical Bulletin”, 2009. The second volume of the Ukrainian authorized translation of the 22nd German edition of Johannes Sobotta’s Atlas of Human Anatomy presents modern data and describes in detail the structure of the torso, internal organs and lower extremity. Along with the anatomical illustrations, images are presented, which are obtained with the help of high-tech methods of lifelong research (radiographs, computed tomograms, magnetic resonance imaging, etc.), which provides a comparative presentation of the material and clinical focus of the atlas. All anatomical terms correspond to the modern International anatomical nomenclature – the Ukrainian standard (Kiev, 2001). The atlas is intended for students and teachers of higher medical educational institutions of the I V level of accreditation, doctors, employees and a wide range of interested teachers.
	Human anatomical atlas: Per. from the 8th English. ed. / Responsible for design and lustration William Ober; scientific editor VG Cherkasov. – VSV “Medicine”, 2011. – 128p.; 250 il. The creation of the atlas was based on “Fundamental Anatomy and Physiology”, the eighth edition. The illustrations in the atlas are arranged by body parts. In key areas, they are supplemented by photographs of the autopsy, and thus to the medical scan of a living person. For students of higher medical educational institutions of the I V level of accreditation.

Publishing activities (textbooks, monographs with short annotations, general figures, photos of textbooks, monographs, links to information resources)

№ Name Nature of work Initial data Volume

(p.) Co-authors

Author’s certificates, diplomas, patents

1 The use of lactoprotein with sorbitol as a marker of permeability of blood capillaries of internal organs in burns Patent of Ukraine for a utility model Patent № 92234, Ukraine, IPC 2014.01.

// Application № 4201401507; declared 17.02.14; publ. 11.08.2014, Bull. № 15.:– 8 p. 8 Gunas IV,

Cherkasov EV

2 Method for evaluating the effectiveness of treatment of burn disease Ukrainian patent for utility model Patent for utility model № 103898, Ukraine.

IPC 2015.01.

10 s. 10 Gunas IV,

Cherkasov EV

Cherkasov VG

3 Educational and methodical manual “Human Anatomy (control over independent preparation for practical classes) / Edition 9-e. – Kyiv: 2017. – 157 p. Author’s certificate Certificate of registration of the author’s certificate for the work

№ 77238

157 Cherkasov VG, Kovalchuk OI

4 Training manual “Human Anatomy” “Module -1 – Anatomy of the musculoskeletal system” Author’s certificate Certificate of registration of copyright to the work № 53170.

Date of registration: 17.01.2014. 69 Cherkasov VG,

Kovalchuk OI

5 Training manual “Human Anatomy” “Module -2 – Splanchnology. Central nervous system. Sense organs »Copyright certificate Certificate of registration of copyright to a work № 53169.

Date of registration: 17.01.2014. 56 Cherkasov VG,

Kovalchuk OI

6 Textbook “Human Anatomy” “Module -3 – Heart. Vessels and nerves of the head, neck. Torso and limbs »Copyright certificate Certificate of registration of copyright to the work № 59462.

Date of registration: 28.04.2015 Cherkasov VG,

Kovalchuk OI

7 Educational and methodical manual for students of higher medical and pharmaceutical educational institutions of Ukraine on control of independent preparation for practical classes on human anatomy Author’s certificate Certificate of registration of copyright to the work № 22515.

Date of registration: 31.10.2007. 174 Cherkasov VG,

Kovalchuk OI

8 Educational and methodical manual “Test tasks” STEP-1 “-human anatomy Author’s certificate Certificate of registration of copyright to the work № 5254976.

Date of registration: 10.12.2013. Cherkasov VG,

Kovalchuk OI

9 Training manual “Human Anatomy. Human anatomy »

Date of registration: 09/21/2018. Cherkasov VG,

Kovalchuk OI

1 Manual “Human Anatomy (control over self-preparation for practical classes)

Author’s certificate Certificate of registration of the author’s certificate for the work

№ 77238

Cherkasov VG, Dzevulskaya IV

2 Textbook “Human Anatomy. Volume 1 /

6th edition, revised – Vinnytsia: New book, 2017. – 368 p. Author’s certificate Certificate of registration of the author’s certificate for the work № 77285

Holovatsky AS,

Cherkasov VG, Sapin MR, Parakhin AI

3 Textbook “Human Anatomy. Volume 2 / 5th edition, revised – Vinnytsia: New book, 2017. – 456 p. Author’s certificate Certificate of registration of the author’s certificate for the work № 77284

Golovatsky AS, Cherkasov VG, Sapin MR, Parakhin AI

4 Textbook “Human Anatomy. Volume 3 / 4th edition, revised – Vinnytsia: New book, 2017. – 376 p. Author’s certificate Certificate of registration of the author’s certificate for the work № 77286

Golovatsky AS, Cherkasov VG, Sapin MR, Parakhin AI

1 Manual “Human Anatomy (control over self-preparation for practical classes)

Author’s certificate Certificate of registration of the author’s certificate for the work

№ 77238

Cherkasov VG, Dzevulskaya IV

2 Textbook “Human Anatomy. Volume 1 /

6th edition, revised – Vinnytsia: New book, 2017. – 368 p. Author’s certificate Certificate of registration of the author’s certificate for the work № 77285

Holovatsky AS,

Cherkasov VG, Sapin MR, Parakhin AI

Golovatsky AS, Cherkasov VG, Sapin MR, Parakhin AI

№ Name Nature of work Initial data Volume

(p.) Co-authors

Scientific works on the profile of the department,

Anatomical research in the works of Leonardo da Vinci article Ukrainian Scientific and Medical Youth Journal, 2013, №4 (76). – P. 68–71.

Professional edition 4 О.В. Malikov,

V.G. Cherkasov,

V.L. Goncharov Dzevulska IV

Morphological changes of the pituitary-adrenal system of rats in thermal trauma article. Ukrainian Scientific and Medical Youth Journal, 2013, №4 (76). – P. 9 – 15

Professional edition 7 О.І. Kovalchuk

V.G. Cherkasov Dzevulska IV

VM Titarenko,

О.В. Malikov

Structural changes of the organs of the neuroimmunoendocrine system in burn disease under the conditions of its treatment by intravenous infusion of hyperosmolar solutions

article “Ukrainian morphological almanac” .2013. – Vol.11 №4.– P. 92–98

Professional edition 7 І.В. Gunas

OB Kondratsky

E.V. Cherkasov and Dzevulskaya IV

1 Structural mechanisms of cytoprotection in internal organs during infusion therapy of burn disease Article

The journal is indexed by the international scientometric databases Science Index (eLibrary) and Bibliometrics of Ukrainian Science. Biomedical and biosocial anthropology. – 2014. – №23 – P. 6– 12.

Professional Edition

7 V.G. Cherkasov,

OI Kovalchuk

E.V. Cherkasov and others.

Only 6 people

Structural mechanisms of cytoprotection in the pituitary and adrenal glands in experimental burn disease in rats under the conditions of its treatment by intravenous infusion therapy thesis Ukrainian Scientific and Medical Youth Journal. – 2014, Special issue №.4 (83). – P.137– 138.

Professional edition 2 R.V. Видерко

OI Kovalchuk

V.G. Cherkasov, Dzevulska IV

Influence of combined hyperosmolar solutions on nanoprocesses in the wall of blood capillaries and in the interstitial matrix of internal organs in burn disease article Ukrainian scientific-medical youth journal. – 2014, Special issue №.2 (81). – P. 5– 10.

Professional edition 6 О.І. Kovalchuk

E.V. Черкасов

VG Cherkasov and others.

Only 7 people

Structural features of adaptation and compensation of the broken functions of internals at infusion therapy of a burn disease article

Web of Science World of Medicine and Biology. – 2014. – №4 (46). – P.165–170.

Web of Science 6 VG Cherkasov

OI Kovalchuk

E.V. Cherkasov and others.

Only 7 people

The role of endogenous intoxication in the morphogenesis of changes in the internal organs in the infusion therapy of burn disease article The journal is indexed by the international scientometric databases Science Index (eLibrary) and Bibliometrics of Ukrainian science. Biomedical and biosocial anthropology. – 2015. – № 24 – P. 30 – 36

Professional edition 6 VG Cherkasov

IV Gunas

A.I. Kovalchuk and others.

Only 8 people

Ultrastructural transformations of intercellular substance in internal organs at treatment of a burn disease by infusion of the combined hyperosmolar solutions article Clinical anatomy and operative surgery. – 2015. – Vol.14, №1 (51) .– P. 37 – 44.

Professional edition 9 VG Cherkasov

IV Gunas

OI Kovalchuk and others.

Only 8 people

Morphological changes of the pituitary-adrenal system of rats in thermal trauma article Ukrainian Scientific and Medical Youth Journal, 2013, №4 (76). – P. 9 – 15

Professional edition 7 О.І. Kovalchuk

VG Cherkasov

V.M. Tytarenko and others.

Only 4 people.

Educational complex for studying the discipline of human anatomy in medical universities

article Medical education. – 2015, – №. 3. – P. 86– 9 Professional edition 0 4 V.G. Черкасов

OI Kovalchuk

І.О. Tymoshenko

Anatomical lecture as an important means of forming corporate academic culture article Medical education. – 2015, №. 3. – P. 90 – 94 Professional edition 5 VG Cherkasov

L.I. Ostapyuk

OI Kovalchuk

Microscopic picture of the adrenal glands during the month in rats, which during the first seven days were injected with a solution of HAES-LX-5% article “Bulletin of morphology.” – 2015, «. 1 (Vol. 21). – P. 81 – 83

Professional edition 3

Ultrastructural changes in the endothelium of blood capillaries of internal organs in experimental burn disease by infusion of combined hyperosmolar solutions article “Bulletin of morphology”. – 2015, «. 1 (Vol. 21). – P. 96 – 102

Professional edition 7 VG Cherkasov

OI Kovalchuk

E.V. Cherkasov and others.

Only 7 people

Evaluation of the effect of infusion of composite hyperosmolar solutions on the structure of neuroimmunoendocrine system organs in burn diseas article European International Journal of Science and Technology– (December), 2015

Vol.4, № 9. – P. 51– 61. 11 Viktor G. Cherkasov Aleksandr I. Kovalchuk,

Eldar V. Cherkasov

Morphological aspects of cytoprotection in the organs of the neuroimmunoendocrine system in infusion ternapii burn disease article World of Problems of Biology and Medicine – 2015, Issue 4, Volume 2 (125). – P. 310 – 316.

Professional Edition

7 VG Cherkasov

OI Kovalchuk

E.V. Cherkasov Dzevulska IV

Morphological effects of infusion of hyperosmolar solutions in skin burn injury article Scientific Bulletin of Uzhgorod National University. – 2015. – Issue 2 (52) – P. 30–37

Professional edition 8 VG Cherkasov

OI Kovalchuk

E.V.

№ s / n Surname and initials of the employee (Ukrainian and English) Age

employee

Index Worse than Scopus

Link to profile in Scopus

Profile link

Orcid.org Index Worse than Google Scholar Link to profile in Google Scholar (Last name and first name in profile) Index Worse than Web of Science Link to profile in Web of Science (Web of Science Researcher

ID)

Cherkasov VG (ViktorCherkasov)

66 1 https://www.scopus.com/authid/detail.uri?authorId=7102973540

https://orcid.org/0000-0002-4645-4695

http://orcid.org/0000-0002-4645-4695

8 Cherkasov Victor Gavrilovich CherkasovVictor

https://scholar.google.com/ua/citations?user=zfaEcDkAAAAJ&hl=en

Web of Science ResearcherID 

I-7509-2018

https://publons.com/researcher/1926946/viktor-cherkasov/

Dzevulskaya IV (DzevulskaIrina) 58 1 https://www.scopus.com/authid/detail.uri?authorId=57201642622

4 DzevulskaIrinaDzevulska Irina Viktorivna

https://scholar.google.com/ua/citations?user=M7m8md8AAAAJ&hl=en

Kovalchuk OI (OleksandrKovalchuk) 41 2 https://www.scopus.com/authid/detail.uri?authorId=35114967200

https://orcid.org 0000-0002-6311-3518

http://orcid.org/0000-0002-6311-3518

5 OleksandrKovalchuk = Kovalchuk Alexander Ivanovich = OI Kovalchuk

https://scholar.google.com/ua/citations?user=mu5lI6UAAAAJ&hl=en

Web of Science ResearcherID 

K-9993-2015

https://publons.com/researcher/1374916/oleksandr-kovalchuk/

Ostapyuk LI

(Ostapyk Lybov) 78 4 https://scholar.google.com/citations?user=B6NCPIIAAAAJ&hl=en

Malikov OV (OV Malikov)

41 http://orcid.org/0000-0002-8113-2974

3 https://scholar.google.com/ua/citations?user=E74uCHMAAAAJ&hl=en

Kaminsky RF 39 2 https://www.scopus.com/authid/detail.uri?authorId=57201551313

https://orcid.org/0000-0001-5744-7581

2 KaminskiyRostislav = Kaminskiy Rostislav

https://scholar.google.com/ua/citations?user=gSHq4qgAAAAJ&hl=ru&oi=ao

Web of Science ResearcherID 

E-1538-2019

https://publons.com/researcher/1779849/rostislav-f-kaminsky/

Tymoshenko IO (Iryna Tymoshenko 29 https://orcid.org/0000-0002-1580-3362

1 Irina Tymoshenko – TymoshenkoIryna

https://scholar.google.com/ua/citations?hl=en&user=aYZxq-EAAAAJ&view_op=list_works&sortby=title

Lakhtadir TV (Lachtadyr Tetiana) 36 https://orcid.org/0000-0003-0223-4866

2 https://scholar.google.com/citations?user=c1GDGH8AAAAJ&hl=en

https://publons.com/researcher/2961070/tetiana-lachtadyr/